Pesticide Resistance Mechanisms

Le Goff, G., Boundy, S., Daborn, P. J., Yen, J. L., Sofer, L., Lind, R., Sabourault, C., Madi. Ravazzi, L., ffrench-Constant, R. H., et al. (2003). Micro soldiers analysis of P450 mediated insecticide pipework in Drosophila. Insect Biochemistry and Molecular Biology, 33(7), 701708. Insecticide justification has been associated with the regulation of some(prenominal) P450 genes by using both demesne and laboratory differentiate D. melanogaster and D. simulans resistant Drosophila sifts. In the laboratory, the authors were able to co get for the over transcription of the gene Cyp12d1 in a billet that had already over transcribed the gene Cyp6g1. They also selected a strain moreover over expressing the Cyp6a8 gene. Selection of these different genes was do by genetic mapping of the associated pesticide resistor, which mapped to locations on chromosome II. However, it was found that the rampart in both D. melanogaster and D. simulans is associated primarily with the over transcription of Cyp6g1. Cyp12d1 and Cyp6a8 could plainly confer resistant to a few of the pesticides used, imidacloprid and malathion, while Cyp6g1 showed ohmic oppositeness to all of the pesticides that was used on the gene (imidacloprid, malathion, acetameprid and nitenpyram).

The authors hypothesis of Cyp6g1 origination more selected due to its ability to metabolise a massivelyr soldiers of pesticides was correct as seen by the same gene conception selected for in both D. melanogaster and D. simulans. The authors showed that different genes can be selected for resistance in the laboratory by using a union insecticide, while only one gene is selected for in vaul! t of heaven populations using multiple insecticides. This led them to conclude that genes conferring a wide range of cross resistance, such as Cyp6g1, can be selected for by a wider array of compounds, increasing its selection as a resistance gene. Feyereisen, R. (1995). Molecular biology of insecticide resistance. Toxicology Letters, 82/83, 8390. The continued use of pesticides...If you want to get a full essay, order it on our website: BestEssayCheap.com

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